Postdoctoral Research Scholar (FPO1)

Free Radical and Radiation Biology/Radiation Oncology

General Description:

To participate in the design, execution and control of a laboratory research program that is studying the role of free radicals in cellular proliferation in normal and cancer cells under normal growth conditions and following oxidative stress. To coordinate the processing and analysis of data, coordinate the conduct of experimental tests and procedures and develop new and/or revised research methodologies; will perform experiments to investigate role of free radicals in cell cycle progression; will learn to prepare manuscripts, grant proposals, and presentations for national audiences.

·         Support and conduct research experiments looking at the involvement of free radical-signaling (oxygen and nitrogen species) in cell cycle progression in normal, aging, and cancer in vitro cell culture systems.

·         Responsible for development of experimental designs and procedures for collecting, consolidating and analysis of research data.

·         Assist in providing research support and training for the graduate assistants in the laboratory.

·         Perform critical analysis of literature relevant to this laboratory research program.

·         Participate in the development of general goals for the research project and in the planning of laboratory work plan and coordinate the work of graduate students, and other support personnel; serve as a consultant to the project director.

·         Responsible for the preparation of research papers and presentations at scientific conferences and workshops; the writing of research reports, articles, and other documents.

·         Learn to organize data and write original research proposals for new funding opportunities.

·         Perform experiments using molecular biology methods, flow cytometry assays of free radicals and cell cycle phase distributions, biochemical and EPR assays.

Qualifications:

A Ph.D. in a field of biology closely related to free radicals and antioxidant proteins with technical skills in the areas of antioxidant enzyme assays (catalase, superoxide dismutase, glutathione peroxidase, glutathione reductase, peroxiredoxins), measurement of free radicals, transfection and/or transduction of antioxidant proteins both in vitro and in vivo, mammalian cell culture, cell cycle, clonogenic cell survival assay, molecular biology of antioxidant and prooxidant gene expression, and experience in flow cytometry assays is highly desirable.

Reference:

Check our recent publications in Aging Cell (Doi:10.1111/j.1474-9726.2008.00384.x); Cancer Research, 2007, 67:6392-6399; Oncogene 2007, 26:1101-1109