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Pathology

UI graduate faculty research projects in Pathology currently available to SROP scholars. This list does not represent all faculty interested in being mentors. Please check the Pathology faculty website for additional research interests.

 

Role of Stra6 in Sarcomas

Principal Investigator Yash Pal Agrawal, Assistant Professor
Department(s): Pathology
College of Medicine
Research Description
  1. Learn proteome analysis techniques such as 2-D gel electrophoresis and MALDI-TOF mass spectrometry.
  2. Learn RT-PCR, western blots.
Undergraduate Role Will mostly perform RT-PCR and also real time PCR.
Minimum Qualifications Hard working and self-motivated.
Contact Information 319-335-7244
Yashpal-agrawal@uiowa.edu
Professor Yash Pal Agrawal

NK Cell Activation in Viral Infection

Principal Investigator Jonathan Heusel, Assistant Professor
Department(s): Pathology
Interdisciplinary Programs:  Immunology
College of Medicine
Assistant(s) Colleen Fullenkamp
Research Description To understand the molecular parameters that govern NK cell activation, involving both activating and inhibitory NK cell surface receptors.
Undergraduate Role To work with a senior member of the laboratory on a project with one or two well-defined goals.  Such projects may involve molecular cloning, flow cytometry, and/or cell culture techniques.  Undergraduates would be expected to attend lab meetings and are invited to present their findings at the end of the rotation. 
Minimum Qualifications Successful performance (grade B or higher) in undergraduate biology, biochemistry, or genetics course; highly self motivated applicants are desired. 
Contact Information 335-8217
jon-heusel@uiowa.edu
Jonathan Heusel

Role of Dendritic Cells in Letha and Sublethal Influenza Virus Infections

Principal Investigator Kevin Legge, Assistant Professor
Department(s): Pathology
Interdisciplinary Programs:  Immunology
College of Medicine
Research Description Our lab studies how dendritic cells activate and regulate the adaptive immune response to influenza virus.  In particular we are focused upon how the degree of influenza infection dictates the magnitude and type of CD8 T cell response generated. 
Undergraduate Role The student will work with an experienced member of the lab on one of the lab's ongoing projects. The student will have his/her own goals and objects, and will actively participate in lab meetings. The project may include the use of RT-PCR, realtime RT-PCR, and flow cytometry, and will most likely be focused on determining if dendritic cells are differentially infected during lethal and sublethal influenza virus infections.
Minimum Qualifications Successful performance (grade B or higher) in undergraduate biology, biochemistry, or genetics course.
Contact Information 319-335-6744
kevin-legge@uiowa.edu
Professor Kevin Legge

 

 

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