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Biochemistry

UI faculty research projects in Biochemistry currently available to SROP scholars. This list does not represent all faculty interested in being mentors.  Please check the Biochemistry faculty website for additional research interests.
 

Role of Vinculin in Tumor Cell Invasion and Metatasis

Principal Investigator Kris DeMali, Professor
Department(s): Biochemistry
Interdisciplinary Program(s):  Molecular and Cellular Biology
College of Medicine
Research Description TBA
Undergraduate Role TBA
Minimum Qualifications TBA
Contact Information 335-7882
kris-demali@uiowa.edu
Professor Kris DeMali

 

Control of transcription by P-TEFb

Principal Investigator David Price, Professor
Department(s): Biochemistry
Interdisciplinary Program(s):  Molecular and Cellular Biology
College of Medicine
Research Description Overall, we use biochemical, molecular and cellular techniques to advance our understanding of the control of RNA polymerase II elongation and how that process influences RNA processing, HIV replication and cancer growth.
Undergraduate Role Whatever is needed
Minimum Qualifications Keen interest in research
Contact Information (Telephone) 319-335-7910
(Email address) david-price@uiowa.edu
University website for Professor David Price

The Role of Chromatin Protein in Gene Regulation and Disease

Principal Investigator Lori L. Wallrath, Assistant Professor
Department(s): Biochemistry
Interdisciplinary Program(s):  Molecular Biology
College of Medicine
Research Description The goal of our research is to understand the role of chromatin structure in gene expression. Specifically, we are interested in the role a protein called Heterochromatin Protein 1. We are using the fruit fly Drosophila to study the mechanism of gene regulation by HP1. In collaboration with the lab of Mary Hendrix, we are studying the role of HP1 in metastasis of human breast cancer cells.
Undergraduate Role Use site directed mutagenesis to generate mutations in proteins involved in packaging DNA and regulating gene expression. Use a 2-hybrid system to test for interactions between proteins involved in silencing gene
Minimum Qualifications Course work in Biology necessary. Course work in Genetics and Molecular helpful.
Contact Information (Telephone) 319-335-7920
(Email address) lori-wallrath@uiowa.edu
University website for Professor Lori L. Wallrath

 

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