Mentor
Dr. Chun-Fang Wu
Participation year
2009
Project title

Qvr Mutants and Motors Skills: Flies and Their Ability to Groove Through A Tube

Abstract

The objective of this research is to observe how flies move through vials separated by a sieve and variations due to environmental factors in a fly's ability to go through the sieve. Such information may suggest a category of genes that play a role in their motor skills. The mutant flies in this experiment are qvr1, qvr2, qvr ∆p-6, and qvr∆p-7. CS wild-type flies were the control. Flies were collected and placed in an empty plastic vial with a sieve located above them. On top of the sieve another empty vial was placed to collect the flies that went through the tube. Climbing tests were done to the same flies that went through the sieve test. The remaining flies were sexed and counted so the data could be used for future experiments to see if there is difference in male or female motor skills by genotype. Our results demonstrate a clear distinction between the wild-type flies and all mutant flies for the sieve tests. Wild-type flies went through the sieves at a greater rate than all the mutant genotypes with an average of 45%, qvr∆p-6 flies at 28%, qvr∆p-7 at 23%, qvr1 at 14%, and qvr2 at 3.7%. There was no evidence for population dependency on motor performance in any of the genotypes. The climbing test shows wild-type flies were the fastest to climb with qvr∆p-7, qvr1, qvr∆p-6, and qvr2 following behind in that order. Results indicate that mutations of the qvr gene have an effect on the motor skills of the flies as indicated by their diminished ability to travel through the sieve and to climb.

Keyon  Mitchell
Education
Loyola Marymount University